Facilities
Purdue's Discovery Park
Purdue Institute of Inflammation, Immunology and Infectious Disease (PI4D)
The Purdue Institute of Inflammation, Immunology and Infectious Disease (PI4D), is part of the Life Sciences Initiative at Purdue. PI4D leverages the broad range of expertise in life sciences, physical sciences and engineering, to develop new diagnostics. PI4D assembles teams of investigators to probe basic biology and inflammatory processes, to commercialize novel interventions and methods for controlling an array of chronic inflammatory conditions, cancer and infectious diseases. PI4Ds core strengths are organized into four areas: Infectious Disease, Immunology & Inflammation, Cont. & Intervention, Imaging & Diagnostics.
Purdue Institute for Drug Discovery (PIDD)
Founded in 2013 to leverage Purdue's strengths across all points of the drug-discovery pipeline, the Purdue Institute for Drug Discovery (PIDD) is accelerating the translation of basic research into life-changing treatments. The mission of PIDD is to create an innovative research environment that will stimulate the discovery, synthesis, evaluation and clinical translation of new drugs for the diagnosis and therapy of human diseases.
Bindley Bioseciences Center (BBC)
The Bindley Bioscience Center provides a unique infrastructure to support interdisciplinary research. Laboratory space and high-end scientific equipment is shared and available to support diverse projects, ranging from complex diseases to technology development to new catalysts for biofuels production. An expert staff provides research consultation and technical support to enable technology implementation, feasibility studies, and the generation of pilot data to support new project ideas.
Selected Shared Resources
Purdue Biophysical Analysis Laboratory Core Facility
The Purdue Biophysical Analysis Laboratory Core facility is available for use on campus. This facility houses an iTC200 Isothermal Titration Calorimeter (ITC) for thermodynamic binding measurements, a Biacore 3000 Surface Plasmon Resonance instrument and an Octet Red384 both for kinetic analysis of molecule binding. All instrumentation is available on a fee for service basis and facility is staffed with PhD level personnel available for instrument training, data collection and data analysis.
Purdue Biosciences Imaging Facility
Purdue Biosciences Imaging Facility provides instruments and expertise needed to visualize molecules in preparations ranging from single cells to entire animals. All facility users receive individualized instrument training as well as project specific advice for optimal data acquisition. Consultation on sample preparation, image rendering, and data analysis are also available.
Purdue Chemical Genomics Facility
The Chemical Genomics Facility (CGF) is a facility at the Purdue Institute for Drug Discovery. The mission of the CGF is to provide expertise and resources for investigators from Purdue and others to access to the state-of-art technologies and instrumentation in high-throughput screening (HTS) and high content screen (HCS) to facilitate the identification of chemical tools to study biological pathways and the discovery of lead compounds for the development of novel therapeutics and diagnostic approaches.
The Purdue Cryo-EM Facility is a member of the Purdue EM Consortium and a designated Indiana CTSI Core Facility. Our facility is available to Purdue, other academic institutes, and industry users. It provides state-of-the-art instruments and expertise for high resolution structure determination of viruses, larger macromolecular complexes, nano-particles, as well as tomographic visualization of virus-cell interactions by cryo-electron microscopy (cryo-EM) and three-dimensional (3-D) image reconstruction.
Purdue Flow Cytometry and Cell Separation Facility
The Flow Cytometry and Cell Separation Facility provides advanced cell sorting and cell analysis techniques including immunofluorescence detection of 18 colors, cell-cycle distribution, apoptosis measurements, cytokine detection, data analysis and more. We will train those users interested in running their own samples on the BD Fortessa or the BC FC500. Facility staff will run all experiments on the FACS Aria III. The facility provides expert consultation for protocol development so that experiments are appropriately designed and implemented.